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Adenosine 3’,5’-cyclic
monophosphate (cyclic AMP, cAMP) is one of the most
important “second messengers” involved as a modulator of
physiological processes, such as regulating neuronal,
glandular, cardiovascular, immune mechanism, nervous system,
cell growth and differentiation. A number of hormones (e.g.,
ACTH, TSH, LH) are known to activate cAMP through the action
of the enzyme adenylate cyclase which converts ATP to cAMP.
Guanosine 3,5-cyclic monophosphate (cyclic GMP, cGMP) has
been shown to be present at levels typically 10-100 fold
lower than cAMP in most tissues and is formed by the action
of the enzyme guanylate cyclase on GTP. Some hormones (e.g.,
acetylcholine, insulin, and oxytocin) and chemicals (e.g.,
serotonin and histamine) cause an increase in cGMP levels.
BioVision’s cAMP and cGMP Assay Kits provide recombinant
Protein G coated plate and high affinity anti-cAMP (or Anti-cGMP)
antibody as well as other necessary reagents for an easy and
sensitive quantification of cAMP or cGMP levels. Assay can
be performed directly in a 96-well plate and results can be
analyzed in a microtiter plate reader at 650 nm. The entire
procedure can be done in ~3 hours.
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+32
1658 9045
+32
1650 9045
